Botox Facial New Westminster

Botox Facial New Westminster

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Our experienced professionals use the latest techniques to deliver precise and natural-looking results, minimizing discomfort and downtime.

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Our team is highly trained and experienced, ensuring every procedure is performed with the utmost care. There's minimal downtime involved, allowing most of our clients to return to their normal activities immediately after their appointment. We often encounter misconceptions about Botox, believing it results in an unnatural appearance. One of our clients, Sarah, shared, 'After my sessions at Manhas Health Co., I noticed a significant reduction in my forehead lines. Learn more about Botox Facial New Westminster here
Embarking on the Botox treatment journey at Manhas Health Co., we'll first schedule an in-depth consultation to discuss your goals and examine your skin. New Westminster cosmetic experts The cost of cosmetic Botox varies, depending on the areas treated and the amount of Botox used.

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We've come to appreciate the fine balance between embracing our inherent features and seeking professional assistance to refine them. Booking your appointment is the first step towards embracing the enhanced you. Learn more about Manhas Health Co. here.
Our team's expertise ensures that doses are precise, targeting only the intended muscles, minimizing risks, and maximizing the beauty of natural-looking results. These plans allow you to spread the cost over time, making it easier to budget for your treatment without sacrificing quality and care. First, we've introduced a targeted Botox treatment specifically for forehead wrinkles, a concern many of our clients have voiced. We're here to guide you through the aftercare process and answer any questions, ensuring you're delighted with your rejuvenated skin.
Our specialists are skilled in the precise application of Botox to alleviate migraine symptoms, offering an alternative treatment for those who've found little relief elsewhere. Botox before and after Additionally, staying hydrated and applying any recommended creams or serums can aid in the recovery process. It's about enhancing quality of life in various ways. We understand that each client's journey towards achieving their aesthetic aspirations is unique.

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Starting treatments before deep wrinkles have a chance to set in can maintain a youthful appearance for longer and may reduce the need for more invasive procedures down the line.

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If you'd prefer a more personal touch, we're just a phone call away. This is where frown lines occur, and Botox can significantly reduce these marks of concentration or concern, contributing to a friendlier, more approachable appearance. These stories aren't just about the aesthetic improvements; they're about the newfound confidence and joy our clients experience. Generally, Botox is considered safe when administered by a qualified professional.

By the end of your consultation, you'll have a clear understanding of how Botox can enhance your appearance and the peace of mind that you're in expert hands. To reduce bruising, we advise avoiding alcohol and blood-thinning medications, like aspirin, for a few days before and after your session. We pride ourselves on using only the highest quality Botox, guaranteeing that our clients achieve the natural-looking results they desire. We don't just stop at facial rejuvenation.

We've designed our scheduling system to be flexible, allowing clients to book appointments at times that work best for them, including evenings and weekends. We consider factors like your skin's condition, your age, and your lifestyle to tailor a treatment that's as unique as you are. Furthermore, the convenience doesn't stop at the time it takes to perform the procedure. Applying a broad-spectrum sunscreen daily protects our skin from UV damage, which can diminish the results of our Botox treatment.

At Manhas Health Co., we recognize that every person's skin and aesthetic goals are unique.

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By incorporating these treatments into your care routine, we're not just turning back the clock; we're slowing its ticking, ensuring that your skin remains vibrant and youthful for as long as possible. We're here to guide you through every step, ensuring your journey towards a more youthful and vibrant appearance is smooth and fulfilling. These results last around three to four months, after which you can return for a touch-up.

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Richard Clement Moody arrived in British Columbia in December 1858, at the head of the Royal Engineers, Columbia Detachment, having been hand picked to "found a second England on the shores of the Pacific".  Moody "wanted to build a city of beauty in the wilderness" and planned his city as an iconic visual metaphor for British dominance, "styled and located with the objective of reinforcing the authority of the Crown and of the robe  Subsequent to the enactment of the Pre-emption Act of 1860, Moody settled the Lower Mainland and selected the site and founded the new capital, New Westminster. Moody and the Royal Engineers were trained in settlement and selected the site because of its defensibility: it was farther from the American border than the site of the colony's proclamation, Fort Langley, possessed "great facilities for communication by water, as well as by future great trunk railways into the interior and possessed an excellent port  Moody was also struck by the majestic beauty of the site, writing in his letter to Blackwood:

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Nearby Tourist Attractions

Burnaby Mountain Conservation Area

Tourist attraction, Park
Burnaby Mountain Conservation Area, 800 Burnaby Mountain Pkwy, Burnaby, BC V5A 1G9
Sprawling natural area with numerous trails, plus carved wooden sculptures popular for sunset snaps.

Annieville Lions Park

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Holland Park

Whalley
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Holland Park, 13428 Old Yale Rd, Surrey, BC V3T 3C7
Public green space equipped with water features, Japanese & Chinese gardens plus sport courts.

Citations and other links

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At Manhas Health Co., we're committed to providing answers and personalized care, ensuring that each client's journey towards a fresher facade is both informed and comfortable. They've shared how these procedures haven't just rejuvenated their appearance but also boosted their confidence. During the procedure, we'll use a very fine needle to inject Botox into the targeted muscles. Botox treatments, when administered by the experienced hands at Manhas Health Co., offer a spectrum of benefits, from smoothing out fine lines to preventing deeper wrinkles from taking root. At Manhas Health Co., we believe that a one-size-fits-all approach doesn't work when it comes to your wellness and aesthetics.

Cosmetic Botox, a popular non-surgical treatment, temporarily smooths facial wrinkles by relaxing the underlying muscles. Botox consultation advice It's about providing care that makes you look and feel your best, without interrupting your life. Our team is committed to offering personalized care that aligns with your beauty goals. You'll need to provide some basic information such as your name, contact number, and any specific concerns or areas you'd like to focus on during your Botox treatment.

They're here not just to perform procedures, but to offer guidance, answer questions, and ensure you feel comfortable and informed every step of the way. Your safety and satisfaction are our top priorities. We're committed to ongoing education and training, ensuring we're always up-to-date with the latest techniques and advancements in the field. We've seen a growing interest in this procedure at Manhas Health Co., where our clients are increasingly eager to rejuvenate their appearance without undergoing invasive surgeries.

This ensures that we can tailor our Botox treatments to fit your unique needs perfectly. Botox for neck lines We've seen firsthand how this mechanism can smooth out fine lines and give our clients a more youthful look. Trust us to provide you with a Botox treatment that not only meets but exceeds your expectations, highlighting your natural beauty in the best possible light. We've all seen the dramatic transformations that can come from cosmetic Botox, like our client Sarah, who discovered a newfound confidence after her treatment at Manhas Health Co. in Botox Facial New Westminster.

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We understand that our clients lead busy lives, and the prospect of a lengthy recovery period can be a significant deterrent. We ensure everyone's safety and satisfaction by using only FDA-approved Botox and having our treatments performed by highly trained professionals. Our experienced professionals use precise techniques to ensure that each treatment is tailored to meet the unique needs of our clients, maximizing the longevity of the results. We understand that every individual's skin is unique, which is why we create tailored treatment plans that align with your specific aesthetic goals.
We also suggest staying upright for four hours post-treatment and avoiding strenuous physical activities for a day. We're here to guide you through every step, from the initial consultation to the post-treatment care, making adjustments as necessary to ensure your complete satisfaction.

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And we're always here to answer any questions, providing a level of care and support that's hard to find elsewhere.
We're here to help you look and feel your best, with a team that's second to none. Read more about Botox Facial New Westminster here We're constantly amazed at how a procedure so simple can have such profound effects. Having explored the broad benefits of Botox, it's clear why Manhas Health Co stands out as the premier choice for your cosmetic needs.
However, like any medical procedure, it carries some risks and potential side effects. It's a fascinating process, really. We'll explore these questions, providing insights into how we can help you achieve a fresher, more vibrant look without sacrificing your natural beauty.

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Recognizing the uniqueness of each individual's needs, we customize every Cosmetic Botox treatment plan to ensure optimal results. We've seen how transformative this treatment can be, not just on the outside, but in how our clients carry themselves with renewed confidence. At Manhas Health Co, we offer a wide range of Botox procedures tailored to meet individual needs and aesthetic goals.

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Understanding that each patient has unique needs, we create personalized Botox treatment plans to achieve the best possible outcomes.

With a professional touch that's neither overzealous nor underwhelming, we've embraced this innovative treatment, recognizing its potential to not only smooth out wrinkles but to also enhance one's self-confidence.

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It's relatively painless, with most clients describing it as a slight pinch.

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We consider your facial structure, skin type, and desired outcomes to craft a personalized treatment plan. Botox and beauty goals

We always emphasize the importance of consulting with our specialists before deciding on Botox. When considering cosmetic Botox at Manhas Health Co, it's vital to know what the journey entails from start to finish. Once you've booked your appointment, we'll send you a confirmation email with all the details you'll need, including any prep instructions for your Botox treatment.

What sets us apart is our commitment to creating a welcoming and supportive environment. Let's help you achieve the results you're looking for with the care and expertise you deserve. Moreover, we're committed to ensuring safety and comfort throughout the process.

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At Manhas Health Co., we believe in providing value that goes beyond the treatment room. These testimonials represent just a fraction of the positive feedback we've received. At Manhas Health Co., we've seen firsthand how Botox can significantly reduce the appearance of wrinkles, offering a more youthful look that our clients love.

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    This holistic view allows us to recommend the most effective, safe, and suitable Botox treatments.

    We're excited for you to see the difference Manhas Health Co. can make in your life. After my treatment at Manhas Health Co., I not only look refreshed but feel a surge of confidence. Booking with us is a breeze, and we've streamlined the process to ensure it's convenient for you.

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    We're committed to providing a safe, comfortable experience for everyone. Botox therapy New Westminster At Manhas Health Co., we're more than just a clinic; we're a community dedicated to helping you look and feel your best. Afterward, you can expect minor swelling or bruising at the injection sites, but these side effects usually subside within a few days.

    Our team of professionals is trained in the latest techniques to ensure that each session is tailored to meet individual needs and expectations. We're here to guide you through each step, ensuring your experience is as comfortable and satisfying as possible. We understand everyone has a busy schedule, so we've made sure to offer appointments throughout the week, including weekends.

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    It's this combination of cutting-edge expertise and personalized care that sets us apart. Botox for facial harmony Our clients' happiness is our top priority, and we're thrilled to see such positive feedback. We're not just providing a service; we're enhancing well-being and self-esteem. Our team, comprised of highly skilled professionals, is the backbone of our success in providing top-notch Cosmetic Botox services. It's important to us that our clients feel informed and confident every step of the way.

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    At Manhas Health Co, we tailor every Botox treatment plan to fit the unique needs and aesthetic goals of our clients. Learn more about Botox Facial New Westminster here By carefully administering Botox in targeted areas, we can significantly reduce sweat production, offering relief and boosted confidence.

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    Military Policlinic in Legionowo, Poland

    A clinic (or outpatient clinic or ambulatory care clinic) is a health facility that is primarily focused on the care of outpatients. Clinics can be privately operated or publicly managed and funded. They typically cover the primary care needs of populations in local communities, in contrast to larger hospitals which offer more specialized treatments and admit inpatients for overnight stays.

    Most commonly, the English word clinic refers to a general practice, run by one or more general practitioners offering small therapeutic treatments, but it can also mean a specialist clinic. Some clinics retain the name "clinic" even while growing into institutions as large as major hospitals or becoming associated with a hospital or medical school.

    Etymology

    [edit]
    The entrance to a surgery clinic in Greenwich, London

    The word clinic derives from Ancient Greek κλίνειν klinein meaning to slope, lean or recline. Hence κλίνη klinē is a couch or bed and κλινικός klinikos is a physician who visits his patients in their beds.[1] In Latin, this became clīnicus.[2][3]

    An early use of the word clinic was "one who receives baptism on a sick bed".[4]

    Overview

    [edit]
    A medpunkt (health care access point) delivers primary health care to the residents of the village of Veliki Vrag, Russia.

    Clinics are often associated with a general medical practice run by one or several general practitioners. Other types of clinics are run by the type of specialist associated with that type: physical therapy clinics by physiotherapists and psychology clinics by clinical psychologists, and so on for each health profession. (This can even hold true for certain services outside the medical field: for example, legal clinics are run by lawyers.)

    Some clinics are operated in-house by employers, government organizations, or hospitals, and some clinical services are outsourced to private corporations which specialize in providing health services. In China, for example, owners of such clinics do not have formal medical education. There were 659,596 village clinics in China in 2011.[5]

    Health care in India, China, Russia and Africa is provided to those regions' vast rural areas by mobile health clinics or roadside dispensaries, some of which integrate traditional medicine. In India these traditional clinics provide ayurvedic medicine and unani herbal medical practice. In each of these countries, traditional medicine tends to be a hereditary practice.

    Function

    [edit]
    Policlinic in Karl-Marx-Stadt, German Democratic Republic

    The function of clinics differs from country to country. For instance, a local general practice run by a single general practitioner provides primary health care and is usually run as a for-profit business by the owner, whereas a government-run specialist clinic may provide subsidized or specialized[dubiousdiscuss] health care.

    Some clinics serve as a place for people with injuries or illnesses to be seen by a triage nurse or other health worker. In these clinics, the injury or illness may not be serious enough to require a visit to an emergency room (ER), but the person can be transferred to one if needed.

    Treatment at these clinics is often less expensive than it would be at a casualty department. Also, unlike an ER these clinics are often not open on a 24/7/365 basis. They sometimes have access to diagnostic equipment such as X-ray machines, especially if the clinic is part of a larger facility. Doctors at such clinics can often refer patients to specialists if the need arises.[6]

    Large outpatient clinics

    [edit]
    Children Policlinic in Novokosino District of Moscow

    Large outpatient clinics vary in size, but can be as large as hospitals.

    Function

    [edit]

    Typical large outpatient clinics house general medical practitioners (GPs) such as doctors and nurses to provide ambulatory care and some acute care services but lack the major surgical and pre- and post-operative care facilities commonly associated with hospitals.

    Policlinic in Vilnius-Karoliniškės, Lithuania

    Besides GPs, if a clinic is a polyclinic, it can house outpatient departments of some medical specialties, such as gynecology, dermatology, ophthalmology, otolaryngology, neurology, pulmonology, cardiology, and endocrinology. In some university cities, polyclinics contain outpatient departments for the entire teaching hospital in one building.

    Internationally

    [edit]
    Policlinic in Písek, Czech Republic

    Large outpatient clinics are a common type of healthcare facility in many countries, including France, Germany (long tradition), Switzerland, and most of the countries of Central and Eastern Europe (often using a mixed Soviet-German model), as well as in former Soviet republics such as Russia and Ukraine;[7] and in many countries across Asia and Africa.[8]

    In Europe, especially in the Central and Eastern Europe, bigger outpatient health centers, commonly in cities and towns, are called policlinics (derived from the word polis, not from poly-).

    Recent[when?] Russian governments have attempted to replace the policlinic model introduced during Soviet times with a more western model. However, this has failed.[9]

    In the Czech Republic, many policlinics were privatized or leasehold and decentralized in the post-communist era: some of them are just lessors and coordinators of a healthcare provided by private doctor's offices in the policlinic building.[10]

    India has also set up huge numbers of polyclinics for former defense personnel. The network envisages 426 polyclinics in 343 districts of the country which will benefit about 33 lakh (3.3 million) ex-servicemen residing in remote and far-flung areas.[11]

    Policlinics are also the backbone of Cuba's primary care system and have been credited with a role in improving that nation's health indicators.[12]

    Mobile clinics

    [edit]
    Hinduja National Hospital's mobile clinic
    A mobile health clinic operated from a truck

    Providing health services through mobile clinics provides accessible healthcare services to these remote areas that have yet to make their way in the politicized space. For example, mobile clinics have proved helpful in dealing with new settlement patterns in Costa Rica. Before foreign aid organizations or the state government became involved in healthcare, Costa Rica's people managed their own health maintenance and protection.[13] People relied on various socio-cultural adaptations and remedies to prevent illnesses, such as personal hygiene and settlement patterns.[13] When new settlements that sprang up along the coast became "artificial" communities, and due to lack of traditional home healing practices here, alternative methods such as mobile clinics had to be implemented in these communities for the protection and prevention of diseases.[13]

    A study done in rural Namibia revealed the health changes of orphans, vulnerable children and non-vulnerable children (OVC) visiting a mobile clinic where health facilities are far from the remote villages.[14] Over 6 months, information on immunization status, diagnosis of anemia, skin and intestinal disorders, nutrition, dental disorders was collected and showed that visits to mobile clinics improved the overall health of children that visited regularly. It concluded that specified "planning of these programs in areas with similarly identified barriers may help correct the health disparities among Namibian OVC and could be a first step in improving child morbidity and mortality in difficult-to-reach rural areas."[14]

    A mobile clinic run from a pickup truck in Yemen

    Food supplementation in the context of routine mobile clinic visits also shows to have improved the nutritional status of children, and it needs further exploration as a way to reduce childhood malnutrition in resource-scarce areas. A cross-sectional study focussed on comparing acute and chronic undernutrition rates prior to and after a food-supplementation program as an adjunct to routine health care for children of migrant workers residing in rural communities in the Dominican Republic.[15] Rates of chronic undernutrition decreased from 33% to 18% after the initiation of the food-supplementation program and shows that the community members attending the mobile clinics are not just passively receiving the information but are incorporating it and helping keep their children nourished.[15]

    Types

    [edit]
    Storefront clinic in Manhattan

    There are many different types of clinics providing outpatient services. Such clinics may be public (government-funded) or private medical practices.

    • A CLSC are in Quebec; they are a type of free clinic funded by the provincial government; they provide service not covered by Canada's healthcare plan including social workers
    • In the United States, a free clinic provides free or low-cost healthcare for those with little or without insurance.
    • A retail-based clinic is housed in supermarkets and similar retail outlets providing walk-in health care, which may be staffed by nurse practitioners.
    • A general out-patient clinic offers general diagnoses or treatments without an overnight stay.
    • A polyclinic or policlinic provides a range of healthcare services (including diagnostics) without need of an overnight stay
    • A specialist clinic provides advanced diagnostic or treatment services for specific diseases or parts of the body. This type contrasts with general out-patient clinics.

    See also

    [edit]

    References

    [edit]
    1. ^ κλινικός in A Greek–English Lexicon. Retrieved 18 September 2016.
    2. ^ clinicus in A Latin Dictionary. Retrieved 18 September 2016.
    3. ^ Partridge, Eric. Origins: A short etymological dictionary of modern English. Book Club Associates, 1966.
    4. ^ Clinic, Webster's Revised Unabridged Dictionary, 1913.
    5. ^ "Statistical Communiqué on the 2011 National Economic and Social Development". stats.gov.cn. National Bureau of Statistics of China. 22 February 2012. Archived from the original on 6 April 2012. Retrieved 5 September 2012.
    6. ^ "Clinic search engine tools to find the right Clinic". 123 clinic. Retrieved 15 December 2016.
    7. ^ NLH – Health Management – Policlinics. Retrieved 3 July 2008.[permanent dead link]
    8. ^ Google
    9. ^ Ershova I, Rider O, Gorelov V (December 2007). "Policlinics in London". Lancet. 370 (9603): 1890–1. doi:10.1016/S0140-6736(07)61793-0. PMID 18068500. S2CID 43512994.
    10. ^ David Rath: Trnitá cesta privatizace českého zdravotnictví, Hospodářské noviny, 10 September 1996
    11. ^ "199 Additional Polyclinics For Ex-Servicemen". The Hindu. Chennai, India. 26 May 2010.
    12. ^ Cuba's primary health care revolution: 30 years on, Bulletin of the World Health Organization
    13. ^ a b c Morgan, Lynn M. (February 1993). Community Participation in Health: The Politics of Primary Care in Costa Rica. doi:10.1017/CBO9780511558092. ISBN 978-0-521-41898-0. Retrieved 8 May 2020. cite book: |website= ignored (help)
    14. ^ a b Aneni, Ehimen; De Beer, Ingrid H.; Hanson, Laura; Rijnen, Bas; Brenan, Alana T.; Feeley, Frank G. (2013). "Mobile primary healthcare services and health outcomes of children in rural Namibia". Rural and Remote Health. 13 (3): 2380. ISSN 1445-6354. PMID 24016257.
    15. ^ a b Parikh, Kavita; Marein-Efron, Gabriela; Huang, Shirley; O'Hare, Geraldine; Finalle, Rodney; Shah, Samir S. (September 2010). "Nutritional Status of Children after a Food-Supplementation Program Integrated with Routine Health Care through Mobile Clinics in Migrant Communities in the Dominican Republic". The American Journal of Tropical Medicine and Hygiene. 83 (3): 559–564. doi:10.4269/ajtmh.2010.09-0485. ISSN 0002-9637. PMC 2929051. PMID 20810820.

    In general, a filler is something that is used to fill gaps. Specialized meanings include:

    Materials

    [edit]
    • Filler (animal food), dietary fiber and other ingredients added to pet foods to provide bulk
    • Filler (materials), particles added to a matrix material, usually to improve its properties
    • Filler (packaging), a machine designed to fill packaging, usually occurs in food packaging
    • Filler metal, metal added in the making of a joint through welding, brazing, or soldering
    • Grain filler, a product that is used to achieve a smooth-textured wood finish
    • Injectable filler, a soft tissue filler injected into the skin to help fill in facial wrinkles
    • Star filler, a plastic insert in computer cables which separates wires

    Media and entertainment

    [edit]
    • Filler (media), in television and other media, material that exists outside the story arc to pad out other material
    • "Filler", song by hardcore punk band Minor Threat, from their debut E.P.

    Other uses

    [edit]

    See also

    [edit]

    Wrinkles on the face and hands are a typical sign of aging

    A wrinkle, also known as a rhytid, is a fold, ridge or crease in an otherwise smooth surface, such as on skin or fabric. Skin wrinkles typically appear as a result of ageing processes such as glycation,[1] habitual sleeping positions,[2] loss of body mass, sun damage,[3] or temporarily, as the result of prolonged immersion in water. Age wrinkling in the skin is promoted by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors.[4] In humans, it can also be prevented to some degree by avoiding excessive solar exposure and through diet (in particular through consumption of carotenoids, tocopherols and flavonoids, vitamins (A, C, D and E), essential omega-3-fatty acids, certain proteins and lactobacilli).[5]

    Skin

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    Causes for aging wrinkles

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    A woman of European origin with facial wrinkles

    Development of facial wrinkles is a kind of fibrosis of the skin. Misrepair-accumulation aging theory suggests that wrinkles develop from incorrect repairs of injured elastic fibers and collagen fibers.[6][7][8] Repeated extensions and compressions of the skin cause repeated injuries of extracellular fibers in derma. During the repairing process, some of the broken elastic fibers and collagen fibers are not regenerated and restored but replaced by altered fibers. When an elastic fiber is broken in an extended state, it may be replaced by a "long" collagen fiber. Accumulation of "long" collagen fibers makes part of the skin looser and stiffer, and as a consequence, a big fold of skin appears. When a "long" collagen is broken in a compressed state, it may be replaced by a "short" collagen fiber. The "shorter" collagen fibers will restrict the extension of "longer" fibers, and make the “long" fibers in a folding state permanently. A small fold, namely a permanent wrinkle, then appears.

    Sleep wrinkles

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    Sleep wrinkles are created and reinforced when the face is compressed against a pillow or bed surface in side or stomach sleeping positions during sleep.[9] They appear in predictable locations due to the underlying superficial musculoaponeurotic system (SMAS), and are usually distinct from wrinkles of facial expression.[10] As with wrinkles of facial expression, sleep wrinkles can deepen and become permanent over time, unless the habitual sleeping positions which cause the wrinkles are altered.[11]

    Water-immersion wrinkling

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    A wrinkled finger after a warm bath

    The wrinkles that occur in skin over prolonged exposure to water are sometimes referred to as pruney fingers or water aging. This is a temporary skin condition where the skin on the palms of the hand or feet becomes wrinkly. This wrinkling response may have imparted an evolutionary benefit by providing improved traction in wet conditions,[12] and a better grasp of wet objects.[13] These results were called into question by a 2014 study that failed to reproduce any improvement of handling wet objects with wrinkled fingertips.[14] However, a 2020 study of gripping efficiency found that wrinkles decreased the force required to grip wet objects by 20%, supporting the traction hypothesis.[15]

    Prior to a 1935 study, the common explanation was based on water absorption in the keratin-laden epithelial skin when immersed in water,[16] causing the skin to expand and resulting in a larger surface area, forcing it to wrinkle. Usually the tips of the fingers and toes are the first to wrinkle because of a thicker layer of keratin and an absence of hairs which secrete the protective oil called sebum.

    Adult sole showing water immersion wrinkling

    In the 1935 study, however, Lewis and Pickering were studying patients with palsy of the median nerve when they discovered that skin wrinkling did not occur in the areas of the patients' skin normally innervated by the damaged nerve. This suggested that the nervous system plays an essential role in wrinkling, so the phenomenon could not be entirely explained simply by water absorption. Recent research shows that wrinkling is related to vasoconstriction.[17][18] Water probably initiates the wrinkling process by altering the balance of electrolytes in the skin as it diffuses into the hands and soles via their many sweat ducts. This could alter the stability of the membranes of the many neurons that synapse on the many blood vessels underneath skin, causing them to fire more rapidly. Increased neuronal firing causes blood vessels to constrict, decreasing the amount of fluid underneath the skin. This decrease in fluid would cause a decrease in tension, causing the skin to become wrinkly.[19]

    This insight resulted in bedside tests for nerve damage and vasoconstriction. Wrinkling is often scored with immersion of the hands for 30 minutes in water or EMLA cream with measurements steps of 5 minutes, and counting the number of visible wrinkles in time. Not all healthy persons have finger wrinkling after immersion, so it would be safe to say that sympathetic function is preserved if finger wrinkling after immersion in water is observed, but if the fingers emerge smooth it cannot be assumed that there is a lesion to the autonomic supply or to the peripheral nerves of the hand.[20]

    Other animals with wrinkles

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    Examples of wrinkles can be found in various animal species that grow loose, excess skin, particularly when they are young. Several breeds of dog, such as the Pug and the Shar Pei, have been bred to exaggerate this trait. In dogs bred for fighting, this is the result of selection for loose skin, which confers a protective advantage.[21]

    Techniques for reducing the appearance of aging wrinkles

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    A man receiving a botox injection

    Current evidence suggests that tretinoin decreases cohesiveness of follicular epithelial cells, although the exact mode of action is unknown. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells.[22] Tretinoin is better known by the brand name Retin-A.

    Topical glycosaminoglycans supplements can help to provide temporary restoration of enzyme balance to slow or prevent matrix breakdown and consequent onset of wrinkle formation. Glycosaminoglycans (GAGs) are produced by the body to maintain structural integrity in tissues and to maintain fluid balance. Hyaluronic acid is a type of GAG that promotes collagen synthesis, repair, and hydration. GAGs serve as a natural moisturizer and lubricant between epidermal cells to inhibit the production of matrix metalloproteinases (MMPs).

    Dermal fillers are injectable products frequently used to correct wrinkles, and other depressions in the skin. They are often a kind of soft tissue designed to enable injection into the skin for purposes of improving the appearance. The most common products are based on hyaluronic acid and calcium hydroxylapatite.

    Botulinum toxin is a neurotoxin protein produced by the bacterium Clostridium botulinum. Botox is a specific form of botulinum toxin manufactured by Allergan for both therapeutic and cosmetic use. Besides its cosmetic application, Botox is used in the treatment of other conditions including migraine headache and cervical dystonia (spasmodic torticollis) (a neuromuscular disorder involving the head and neck).[23]

    Dysport, manufactured by Ipsen, received FDA approval and is now used to treat cervical dystonia as well as glabellar lines in adults. In 2010, another form of botulinum toxin, one free of complexing proteins, became available to Americans. Xeomin received FDA approval for medical indications in 2010 and cosmetic indications in 2011.

    Botulinum toxin treats wrinkles by immobilizing the muscles which cause wrinkles. It is not appropriate for the treatment of all wrinkles; it is indicated for the treatment of glabellar lines (between the eyebrows) in adults. Any other usage is not approved by the FDA and is considered off-label use.

    Laser resurfacing is FDA-cleared skin resurfacing procedure in which lasers are used to improve the condition of the skin.[citation needed] Two types of lasers are used to reduce the appearance of fine lines and wrinkles on the face; laser ablation, which removes thin layers of skin, and nonablative lasers that stimulate collagen production. Nonablative lasers are less effective than ablative ones but they are less invasive and recovery time is short. After the procedure people experience temporary redness, itching and swelling.

    See also

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    References

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    1. ^ Danby, FW (Jul–Aug 2010). "Nutrition and aging skin: sugar and glycation". Clin Dermatol. 4. 28 (4): 409–411. doi:10.1016/j.clindermatol.2010.03.018. PMID 20620757.
    2. ^ American Academy of Dermatology. "Causes of Aging". AgingSkinNet. American Academy of Dermatology. Retrieved 5 March 2013.
    3. ^ Cosmetic Procedures for Wrinkles
    4. ^ Anderson, Laurence. 2006. Looking Good, the Australian guide to skin care, cosmetic medicine and cosmetic surgery. AMPCo. Sydney. ISBN 0-85557-044-X.
    5. ^ Schagen, S. K.; Zampeli, V. A.; Makrantonaki, E.; Zouboulis, C. C. (2012). "Discovering the link between nutrition and skin aging". Dermato-Endocrinology. 4 (3): 298–307. doi:10.4161/derm.22876. PMC 3583891. PMID 23467449.
    6. ^ Wang, Jicun; Michelitsch, Thomas; Wunderlin, Arne; Mahadeva, Ravi (2009). "Aging as a consequence of Misrepair—a novel theory of aging". arXiv:0904.0575 [q-bio.TO].
    7. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Aging as a process of accumulation of Misrepairs". arXiv:1503.07163 [q-bio.TO].
    8. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Tissue fibrosis: a principal evidence for the central role of Misrepairs in aging". arXiv:1505.01376 [q-bio.TO].
    9. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
    10. ^ Fulton, James E.; Gaminchi, F. (1999). "Sleep Lines". Dermatol Surg. 25 (1): 59–62. doi:10.1046/j.1524-4725.1999.08073.x. PMID 9935097.
    11. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247 [246]. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
    12. ^ Mark Changizi; Romann Weber; Ritesh Kotecha; Joseph Palazzo (2011). "Are Wet-Induced Wrinkled Fingers Primate Rain Treads?". Brain, Behavior and Evolution. 77 (4): 286–90. doi:10.1159/000328223. PMID 21701145.
    13. ^ Kareklas, Kyriacos; Nettle, Daniel; Smulders, Tom V (January 9, 2013). "Water-induced finger wrinkles improve handling of wet objects". Biol. Lett. 9 (2): 20120999. doi:10.1098/rsbl.2012.0999. PMC 3639753. PMID 23302867.
    14. ^ Haseleu, Julia; Omerbašić, Damir; Frenzel, Henning; Gross, Manfred; Lewin, Gary R. (2014). Goldreich, Daniel (ed.). "Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objects". PLOS ONE. 9 (1): e84949. Bibcode:2014PLoSO...984949H. doi:10.1371/journal.pone.0084949. PMC 3885627. PMID 24416318.
    15. ^ Davis, N. (8 November 2020). "Water-immersion finger-wrinkling improves grip efficiency in handling wet objects". bioRxiv 10.1101/2020.11.07.372631.
    16. ^ "Dr Karl's Homework – Skin Wrinkles in Water (26/1/2000)". Abc.net.au. 2000-01-26. Retrieved 2019-04-30.
    17. ^ Einar P.V. Wilder-Smith; Adeline Chow (2003). "Water-immersion wrinkeling is due to vasoconstriction". Muscle & Nerve. 27 (3): 307–311. doi:10.1002/mus.10323. PMID 12635117. S2CID 45193684.
    18. ^ Einar P. V. Wilder-Smith (2004). "Water immersion wrinkling". Clinical Autonomic Research. 14 (2): 125–131. doi:10.1007/s10286-004-0172-4. PMID 15095056. S2CID 44938772.
    19. ^ H. Zhai, K.P. Whilem H. L. Maibach (2007). Dermatotoxicology. pp. 280–281.
    20. ^ G Alvarez, J Eurolo; P Canales (1980). "Finger wrinkling after immersion in water". British Medical Journal. 281 (6240): 586–587. doi:10.1136/bmj.281.6240.586-a. PMC 1713922. PMID 7427379.
    21. ^ The Dog Encyclopedia: The Definitive Visual Guide. Penguin. 15 August 2023. p. 84. ISBN 978-0-7440-8513-6.
    22. ^ Stefanaki C, Stratigos A, Katsambas A (June 2005). "Topical retinoids in the treatment of photoaging". J Cosmet Dermatol. 4 (2): 130–4. doi:10.1111/j.1473-2165.2005.40215.x. PMID 17166212. S2CID 44702740.
    23. ^ Brin MF, Lew MF, Adler CH, Comella CL, Factor SA, Jankovic J, O'Brien C, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M (1999). "Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia". Neurology. 53 (7): 1431–8. doi:10.1212/WNL.53.7.1431. PMID 10534247.
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