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After your Forma Face Sculpting session at Manhas Health Co., adopting a regimen that nourishes and protects your skin is crucial. Avoid strenuous exercise, heavy lifting, and sexual activity as advised by your healthcare provider. Pay attention to how well they listen and explain the process, including potential risks and aftercare. Afterward, there's no downtime required. Learn more about Best Botox clinic in New Westminster here. Learn more about Botox Near New Westminster here
Our team is dedicated to guiding you through a transformation that aligns with your unique desires and goals. Imagine a skincare routine so finely tuned to your skin's needs that every day brings you closer to the flawless, age-defying complexion you've always desired.

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At Manhas Health Co., we're not just about making you look good; we're about making you feel your best, using technology that sets new standards in aesthetic care. Your specialist will apply a chemical solution to your skin, which might cause a tingling or burning sensation for a few minutes. The Forma technology utilizes radiofrequency energy to target deep layers of your skin, stimulating collagen production without damaging the surface.
We understand that everyone's skin and body are different, which is why we use these innovative tools to create a customized treatment plan just for you. Their team of experts uses state-of-the-art technology to ensure that you're receiving the most effective treatments available. And if safety concerns have kept you at bay, the following insights into the procedure's safety profile and the care required post-treatment might just change your mind.

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A more defined, sculpted facial contour that not only looks more youthful but feels smoother and firmer to the touch. This modern approach at Manhas Health Co. targets various concerns, from aesthetic changes to functional improvements, ensuring you feel your best. Our expert team at Manhas Health Co. is the backbone of our innovative aesthetic treatments, ensuring you receive personalized care tailored to your unique beauty goals. Morpheus 8 treatment is ideal for individuals seeking to reduce wrinkles, tighten skin, and improve overall skin texture without undergoing invasive surgery. Firstly, avoid sun exposure for at least two weeks before your treatment.

We're not just about surface-level beauty; we aim to enhance your overall quality of life, fostering a positive self-image and well-being that radiates from the inside out. At Manhas Health Co., we understand that each person's skin is unique, which is why we've tailored our facial treatments to meet your individual needs.

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She's not alone in her journey; many echo her sentiments, emphasizing the personal and intimate benefits they've experienced. It takes time for your body to produce collagen, so you'll notice improvements gradually over several weeks.

These usually resolve within a few days. You'll find that it's a quick, minimally invasive process, typically taking less than an hour per session. Embarking on your beauty journey with Manhas Health Co, you'll discover that achieving your goals is a collaborative and enlightening process. Before any procedure, you'll receive a detailed explanation of what to expect, and we'll answer any questions you have, ensuring you're fully informed and comfortable.

They understand that each individual's beauty journey is unique, and they're dedicated to providing customized treatment plans that reflect your personal goals and desires. You're not just another appointment on their calendar; you're a priority, and they're committed to providing you with a comfortable, supportive environment. Those with certain medical conditions affecting the skin or immune system may need to explore other options. And the best part?

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Richard Clement Moody arrived in British Columbia in December 1858, at the head of the Royal Engineers, Columbia Detachment, having been hand picked to "found a second England on the shores of the Pacific".  Moody "wanted to build a city of beauty in the wilderness" and planned his city as an iconic visual metaphor for British dominance, "styled and located with the objective of reinforcing the authority of the Crown and of the robe  Subsequent to the enactment of the Pre-emption Act of 1860, Moody settled the Lower Mainland and selected the site and founded the new capital, New Westminster. Moody and the Royal Engineers were trained in settlement and selected the site because of its defensibility: it was farther from the American border than the site of the colony's proclamation, Fort Langley, possessed "great facilities for communication by water, as well as by future great trunk railways into the interior and possessed an excellent port  Moody was also struck by the majestic beauty of the site, writing in his letter to Blackwood:

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Nearby Tourist Attractions

Mundy Park

Tourist attraction, City park
Mundy Park, 641 Hillcrest St, Coquitlam, BC V3J 6N9
178 acres of forest habitat with 2 lakes, sports facilities, disc golf & an outdoor pool.

Port Moody Station Museum

Tourist attraction, Entertainer, Historical landmark, History museum, Local history museum
Port Moody Station Museum, 2734 Murray St, Port Moody, BC V3H 1X2
Small destination offering local history exhibits & programs in a 1908 train station.

Rocky Point Park

Tourist attraction, City park
Rocky Point Park, 2800 Murray St, Port Moody, BC V3H 1X2
Waterfront recreation area with a pier, pool, skate park, restaurant, playground & boat ramp.

Shoreline Trail

Tourist attraction, City park, Hiking area
Shoreline Trail, 2934 Murray St, Port Moody, BC V3H 1X2
This walking trail along the Burrard Inlet offers sweeping views & allows leashed dogs.

Burnaby Fraser Foreshore Park

Tourist attraction, Park
Burnaby Fraser Foreshore Park, 7751 Fraser Park Dr, Burnaby, BC V5J 5L8
Riverfront park with outdoor gym equipment, dog area, picnic spots & a playground.

Hawthorne Rotary Park

Whalley
Tourist attraction, Park
Hawthorne Rotary Park, 10513 144 St, Surrey, BC V3T 4V4
Residential area park with a playground, spray pad, gardens, trails, picnic shelter & washrooms.

Glenlyon Foreshore Outlook

Tourist attraction, Historical landmark
Glenlyon Foreshore Outlook, 9186 Glenlyon Pkwy, Burnaby, BC V5J 5J8

World Police and Fire Games decoration

Metrotown
Tourist attraction
World Police and Fire Games decoration, 3789 BC-99A, Burnaby, BC V5H 1Y4

Citations and other links

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It's not just about looking younger; it's about boosting your confidence. This innovative treatment tightens and firms your skin, reducing the appearance of fine lines and wrinkles that often betray your years.

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We're all about flexibility and convenience, so pick a time that works best for you. At Manhas Health Co., we're committed to providing you with safe, effective, and personalized aesthetic care. However, like any treatment, there are risks and possible side effects you should be aware of.

A good specialist will ensure you have a realistic understanding of what the treatments can achieve. Our team of experts then crafts a customized plan that aligns with your personal aspirations and lifestyle. Feeling good about your intimate areas can profoundly impact your overall well-being and intimacy. They're perfect for addressing issues like sun damage, acne scars, and uneven skin tone.

Firstly, it's essential to rest and limit your physical activity for a few days. This technique works by stimulating collagen production, improving the vaginal tissue's elasticity and moisture. Your skin is as individual as you are, and it deserves a regimen that reflects that. Botox for brow lift They also specialize in non-surgical face lifts and body contouring, providing you with alternatives to more invasive procedures.

At Manhas Health Co., we're committed to making confidence-boosting aesthetic services accessible to everyone. Well, dermaplaning is safe for most skin types, especially if you're seeking a non-invasive method to brighten your skin and achieve that coveted glow. Our approach is personalized, focusing on your individual features and goals to ensure that your natural charms are highlighted and cherished. You've likely heard whispers of their state-of-the-art clinic, where advanced laser therapy and anti-aging solutions are more than just promise-they're reality.



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You'll notice substantial improvement in skin firmness and a reduction in pore size. This innovative approach heats the skin's underlying network of collagen and elastin fibers. Their community outreach doesn't stop there. With Manhas Health Co., you're not just getting a treatment; you're investing in a healthier, more confident you.

Each photo in our gallery tells a story of confidence regained and self-esteem boosted. This innovative treatment, now offered by Manhas Health Co., is your key to unlocking a more youthful glow without the need for invasive procedures. The success stories from Manhas Health Co. don't just stop at individual experiences.

As you witness the visible improvements, you'll feel a renewed sense of confidence that radiates from within. For example, our laser systems are designed to target specific concerns with utmost accuracy, reducing the risk of side effects. At Manhas Health Co., you're now able to explore these options right in Botox Near New Westminster.

Our specialized treatments, such as the anti-aging facial, hydrating therapy, or detoxifying sessions, offer solutions that target specific concerns, promoting skin health and wellness. It's designed to target and remodel larger areas with precision, without the need for incisions or anesthesia.

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These growth factors signal your skin cells and hair follicles to function optimally, increasing blood supply to the follicles and expanding the hair shaft.

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So, let's explore how these treatments could be your pathway to achieving the radiant skin you've always wanted, while also considering what to expect along the way. You can expect to return to your daily activities shortly after the session ends. Additionally, if you're dealing with urinary incontinence, a frequent concern post-childbirth or with aging, this treatment offers a promising solution.

Take Sarah, for instance, who battled acne scars for years.

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Visit our Before and After Gallery today. Lastly, Evolve-X leverages a fat reduction technique that selectively targets fat cells, breaking them down and allowing your body to naturally process and eliminate them.

They offer thorough consultations to discuss your concerns and desired outcomes, ensuring you're well-informed and comfortable every step of the way. If you prefer the digital route, their user-friendly website allows you to select the service you're interested in, choose your preferred date and time, and submit your booking in just a few clicks. Choosing the right specialist isn't just about credentials; it's about finding someone who prioritizes your safety, understands your aesthetic goals, and provides a high level of patient care.

To maintain your newly sculpted face and extend the youthful glow, it's essential to follow a tailored skincare routine. Hydrated, sun-protected skin responds better to treatments and heals faster afterward. You're also looking at minimal downtime with this non-invasive procedure.

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We take into account your skin type, aesthetic preferences, and overall health to recommend the most effective treatments. Initially, you might notice your skin's texture seems tired, with fine lines, wrinkles, and perhaps a bit of sagging that makes you feel less than your best. The best part? The IPL photo facial results can emerge gradually, revealing clearer, more radiant skin over time. Botox for migraines While focusing on recovery and care after your vaginal rejuvenation is essential, it's also important to be aware of the safety concerns and potential risks associated with the procedure.

Delving into the core of its functionality, the technology powering Evolve-X harnesses a trio of advanced techniques to sculpt your body with precision and care. With fillers, you're not just transforming your appearance; you're boosting your confidence and taking a step towards the best version of yourself. This boost in collagen means fine lines and wrinkles can become less noticeable, giving you a more rejuvenated appearance. It's crucial to have these sessions spaced out to catch all hair in its growth phase.

They're on a mission to blend cutting-edge technology with holistic health practices to not only enhance your appearance but improve your overall well-being. Our expert team is ready to guide you through a journey of self-discovery and confidence-building, offering ongoing support and care every step of the way. These platelets are rich in growth factors, substances that signal your cells to function and repair more effectively.

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Moreover, the device is designed to automatically adjust the energy delivery if it senses that the skin temperature is too high. You won't need anesthesia, as the procedure is relatively painless, with most clients reporting only a slight warming sensation. Imagine the possibilities for your own journey towards a more confident and radiant you.

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Our team uses this information to craft a tailored plan that aligns with your vision and ensures the outcomes you're aiming for. Ideally, this treatment is tailored for women who've experienced changes in their vaginal health due to childbirth, aging, or hormonal variations. It's a holistic approach to body sculpting, where fat reduction, skin tightening, and muscle enhancement come together to sculpt a version of you that reflects your inner vitality and zest for life. Whether you're looking to reduce signs of aging, improve skin texture, or contour your body shape, our state-of-the-art technology makes it possible.

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Imagine walking out with a refreshed, more youthful appearance that feels as natural as it looks.
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Military Policlinic in Legionowo, Poland

A clinic (or outpatient clinic or ambulatory care clinic) is a health facility that is primarily focused on the care of outpatients. Clinics can be privately operated or publicly managed and funded. They typically cover the primary care needs of populations in local communities, in contrast to larger hospitals which offer more specialized treatments and admit inpatients for overnight stays.

Most commonly, the English word clinic refers to a general practice, run by one or more general practitioners offering small therapeutic treatments, but it can also mean a specialist clinic. Some clinics retain the name "clinic" even while growing into institutions as large as major hospitals or becoming associated with a hospital or medical school.

Etymology

[edit]
The entrance to a surgery clinic in Greenwich, London

The word clinic derives from Ancient Greek κλίνειν klinein meaning to slope, lean or recline. Hence κλίνη klinē is a couch or bed and κλινικός klinikos is a physician who visits his patients in their beds.[1] In Latin, this became clīnicus.[2][3]

An early use of the word clinic was "one who receives baptism on a sick bed".[4]

Overview

[edit]
A medpunkt (health care access point) delivers primary health care to the residents of the village of Veliki Vrag, Russia.

Clinics are often associated with a general medical practice run by one or several general practitioners. Other types of clinics are run by the type of specialist associated with that type: physical therapy clinics by physiotherapists and psychology clinics by clinical psychologists, and so on for each health profession. (This can even hold true for certain services outside the medical field: for example, legal clinics are run by lawyers.)

Some clinics are operated in-house by employers, government organizations, or hospitals, and some clinical services are outsourced to private corporations which specialize in providing health services. In China, for example, owners of such clinics do not have formal medical education. There were 659,596 village clinics in China in 2011.[5]

Health care in India, China, Russia and Africa is provided to those regions' vast rural areas by mobile health clinics or roadside dispensaries, some of which integrate traditional medicine. In India these traditional clinics provide ayurvedic medicine and unani herbal medical practice. In each of these countries, traditional medicine tends to be a hereditary practice.

Function

[edit]
Policlinic in Karl-Marx-Stadt, German Democratic Republic

The function of clinics differs from country to country. For instance, a local general practice run by a single general practitioner provides primary health care and is usually run as a for-profit business by the owner, whereas a government-run specialist clinic may provide subsidized or specialized[dubiousdiscuss] health care.

Some clinics serve as a place for people with injuries or illnesses to be seen by a triage nurse or other health worker. In these clinics, the injury or illness may not be serious enough to require a visit to an emergency room (ER), but the person can be transferred to one if needed.

Treatment at these clinics is often less expensive than it would be at a casualty department. Also, unlike an ER these clinics are often not open on a 24/7/365 basis. They sometimes have access to diagnostic equipment such as X-ray machines, especially if the clinic is part of a larger facility. Doctors at such clinics can often refer patients to specialists if the need arises.[6]

Large outpatient clinics

[edit]
Children Policlinic in Novokosino District of Moscow

Large outpatient clinics vary in size, but can be as large as hospitals.

Function

[edit]

Typical large outpatient clinics house general medical practitioners (GPs) such as doctors and nurses to provide ambulatory care and some acute care services but lack the major surgical and pre- and post-operative care facilities commonly associated with hospitals.

Policlinic in Vilnius-Karoliniškės, Lithuania

Besides GPs, if a clinic is a polyclinic, it can house outpatient departments of some medical specialties, such as gynecology, dermatology, ophthalmology, otolaryngology, neurology, pulmonology, cardiology, and endocrinology. In some university cities, polyclinics contain outpatient departments for the entire teaching hospital in one building.

Internationally

[edit]
Policlinic in Písek, Czech Republic

Large outpatient clinics are a common type of healthcare facility in many countries, including France, Germany (long tradition), Switzerland, and most of the countries of Central and Eastern Europe (often using a mixed Soviet-German model), as well as in former Soviet republics such as Russia and Ukraine;[7] and in many countries across Asia and Africa.[8]

In Europe, especially in the Central and Eastern Europe, bigger outpatient health centers, commonly in cities and towns, are called policlinics (derived from the word polis, not from poly-).

Recent[when?] Russian governments have attempted to replace the policlinic model introduced during Soviet times with a more western model. However, this has failed.[9]

In the Czech Republic, many policlinics were privatized or leasehold and decentralized in the post-communist era: some of them are just lessors and coordinators of a healthcare provided by private doctor's offices in the policlinic building.[10]

India has also set up huge numbers of polyclinics for former defense personnel. The network envisages 426 polyclinics in 343 districts of the country which will benefit about 33 lakh (3.3 million) ex-servicemen residing in remote and far-flung areas.[11]

Policlinics are also the backbone of Cuba's primary care system and have been credited with a role in improving that nation's health indicators.[12]

Mobile clinics

[edit]
Hinduja National Hospital's mobile clinic
A mobile health clinic operated from a truck

Providing health services through mobile clinics provides accessible healthcare services to these remote areas that have yet to make their way in the politicized space. For example, mobile clinics have proved helpful in dealing with new settlement patterns in Costa Rica. Before foreign aid organizations or the state government became involved in healthcare, Costa Rica's people managed their own health maintenance and protection.[13] People relied on various socio-cultural adaptations and remedies to prevent illnesses, such as personal hygiene and settlement patterns.[13] When new settlements that sprang up along the coast became "artificial" communities, and due to lack of traditional home healing practices here, alternative methods such as mobile clinics had to be implemented in these communities for the protection and prevention of diseases.[13]

A study done in rural Namibia revealed the health changes of orphans, vulnerable children and non-vulnerable children (OVC) visiting a mobile clinic where health facilities are far from the remote villages.[14] Over 6 months, information on immunization status, diagnosis of anemia, skin and intestinal disorders, nutrition, dental disorders was collected and showed that visits to mobile clinics improved the overall health of children that visited regularly. It concluded that specified "planning of these programs in areas with similarly identified barriers may help correct the health disparities among Namibian OVC and could be a first step in improving child morbidity and mortality in difficult-to-reach rural areas."[14]

A mobile clinic run from a pickup truck in Yemen

Food supplementation in the context of routine mobile clinic visits also shows to have improved the nutritional status of children, and it needs further exploration as a way to reduce childhood malnutrition in resource-scarce areas. A cross-sectional study focussed on comparing acute and chronic undernutrition rates prior to and after a food-supplementation program as an adjunct to routine health care for children of migrant workers residing in rural communities in the Dominican Republic.[15] Rates of chronic undernutrition decreased from 33% to 18% after the initiation of the food-supplementation program and shows that the community members attending the mobile clinics are not just passively receiving the information but are incorporating it and helping keep their children nourished.[15]

Types

[edit]
Storefront clinic in Manhattan

There are many different types of clinics providing outpatient services. Such clinics may be public (government-funded) or private medical practices.

  • A CLSC are in Quebec; they are a type of free clinic funded by the provincial government; they provide service not covered by Canada's healthcare plan including social workers
  • In the United States, a free clinic provides free or low-cost healthcare for those with little or without insurance.
  • A retail-based clinic is housed in supermarkets and similar retail outlets providing walk-in health care, which may be staffed by nurse practitioners.
  • A general out-patient clinic offers general diagnoses or treatments without an overnight stay.
  • A polyclinic or policlinic provides a range of healthcare services (including diagnostics) without need of an overnight stay
  • A specialist clinic provides advanced diagnostic or treatment services for specific diseases or parts of the body. This type contrasts with general out-patient clinics.

See also

[edit]

References

[edit]
  1. ^ κλινικός in A Greek–English Lexicon. Retrieved 18 September 2016.
  2. ^ clinicus in A Latin Dictionary. Retrieved 18 September 2016.
  3. ^ Partridge, Eric. Origins: A short etymological dictionary of modern English. Book Club Associates, 1966.
  4. ^ Clinic, Webster's Revised Unabridged Dictionary, 1913.
  5. ^ "Statistical Communiqué on the 2011 National Economic and Social Development". stats.gov.cn. National Bureau of Statistics of China. 22 February 2012. Archived from the original on 6 April 2012. Retrieved 5 September 2012.
  6. ^ "Clinic search engine tools to find the right Clinic". 123 clinic. Retrieved 15 December 2016.
  7. ^ NLH – Health Management – Policlinics. Retrieved 3 July 2008.[permanent dead link]
  8. ^ Google
  9. ^ Ershova I, Rider O, Gorelov V (December 2007). "Policlinics in London". Lancet. 370 (9603): 1890–1. doi:10.1016/S0140-6736(07)61793-0. PMID 18068500. S2CID 43512994.
  10. ^ David Rath: Trnitá cesta privatizace českého zdravotnictví, Hospodářské noviny, 10 September 1996
  11. ^ "199 Additional Polyclinics For Ex-Servicemen". The Hindu. Chennai, India. 26 May 2010.
  12. ^ Cuba's primary health care revolution: 30 years on, Bulletin of the World Health Organization
  13. ^ a b c Morgan, Lynn M. (February 1993). Community Participation in Health: The Politics of Primary Care in Costa Rica. doi:10.1017/CBO9780511558092. ISBN 978-0-521-41898-0. Retrieved 8 May 2020. cite book: |website= ignored (help)
  14. ^ a b Aneni, Ehimen; De Beer, Ingrid H.; Hanson, Laura; Rijnen, Bas; Brenan, Alana T.; Feeley, Frank G. (2013). "Mobile primary healthcare services and health outcomes of children in rural Namibia". Rural and Remote Health. 13 (3): 2380. ISSN 1445-6354. PMID 24016257.
  15. ^ a b Parikh, Kavita; Marein-Efron, Gabriela; Huang, Shirley; O'Hare, Geraldine; Finalle, Rodney; Shah, Samir S. (September 2010). "Nutritional Status of Children after a Food-Supplementation Program Integrated with Routine Health Care through Mobile Clinics in Migrant Communities in the Dominican Republic". The American Journal of Tropical Medicine and Hygiene. 83 (3): 559–564. doi:10.4269/ajtmh.2010.09-0485. ISSN 0002-9637. PMC 2929051. PMID 20810820.

In general, a filler is something that is used to fill gaps. Specialized meanings include:

Materials

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  • Filler (animal food), dietary fiber and other ingredients added to pet foods to provide bulk
  • Filler (materials), particles added to a matrix material, usually to improve its properties
  • Filler (packaging), a machine designed to fill packaging, usually occurs in food packaging
  • Filler metal, metal added in the making of a joint through welding, brazing, or soldering
  • Grain filler, a product that is used to achieve a smooth-textured wood finish
  • Injectable filler, a soft tissue filler injected into the skin to help fill in facial wrinkles
  • Star filler, a plastic insert in computer cables which separates wires

Media and entertainment

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  • Filler (media), in television and other media, material that exists outside the story arc to pad out other material
  • "Filler", song by hardcore punk band Minor Threat, from their debut E.P.

Other uses

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See also

[edit]

Wrinkles on the face and hands are a typical sign of aging

A wrinkle, also known as a rhytid, is a fold, ridge or crease in an otherwise smooth surface, such as on skin or fabric. Skin wrinkles typically appear as a result of ageing processes such as glycation,[1] habitual sleeping positions,[2] loss of body mass, sun damage,[3] or temporarily, as the result of prolonged immersion in water. Age wrinkling in the skin is promoted by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors.[4] In humans, it can also be prevented to some degree by avoiding excessive solar exposure and through diet (in particular through consumption of carotenoids, tocopherols and flavonoids, vitamins (A, C, D and E), essential omega-3-fatty acids, certain proteins and lactobacilli).[5]

Skin

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Causes for aging wrinkles

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A woman of European origin with facial wrinkles

Development of facial wrinkles is a kind of fibrosis of the skin. Misrepair-accumulation aging theory suggests that wrinkles develop from incorrect repairs of injured elastic fibers and collagen fibers.[6][7][8] Repeated extensions and compressions of the skin cause repeated injuries of extracellular fibers in derma. During the repairing process, some of the broken elastic fibers and collagen fibers are not regenerated and restored but replaced by altered fibers. When an elastic fiber is broken in an extended state, it may be replaced by a "long" collagen fiber. Accumulation of "long" collagen fibers makes part of the skin looser and stiffer, and as a consequence, a big fold of skin appears. When a "long" collagen is broken in a compressed state, it may be replaced by a "short" collagen fiber. The "shorter" collagen fibers will restrict the extension of "longer" fibers, and make the “long" fibers in a folding state permanently. A small fold, namely a permanent wrinkle, then appears.

Sleep wrinkles

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Sleep wrinkles are created and reinforced when the face is compressed against a pillow or bed surface in side or stomach sleeping positions during sleep.[9] They appear in predictable locations due to the underlying superficial musculoaponeurotic system (SMAS), and are usually distinct from wrinkles of facial expression.[10] As with wrinkles of facial expression, sleep wrinkles can deepen and become permanent over time, unless the habitual sleeping positions which cause the wrinkles are altered.[11]

Water-immersion wrinkling

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A wrinkled finger after a warm bath

The wrinkles that occur in skin over prolonged exposure to water are sometimes referred to as pruney fingers or water aging. This is a temporary skin condition where the skin on the palms of the hand or feet becomes wrinkly. This wrinkling response may have imparted an evolutionary benefit by providing improved traction in wet conditions,[12] and a better grasp of wet objects.[13] These results were called into question by a 2014 study that failed to reproduce any improvement of handling wet objects with wrinkled fingertips.[14] However, a 2020 study of gripping efficiency found that wrinkles decreased the force required to grip wet objects by 20%, supporting the traction hypothesis.[15]

Prior to a 1935 study, the common explanation was based on water absorption in the keratin-laden epithelial skin when immersed in water,[16] causing the skin to expand and resulting in a larger surface area, forcing it to wrinkle. Usually the tips of the fingers and toes are the first to wrinkle because of a thicker layer of keratin and an absence of hairs which secrete the protective oil called sebum.

Adult sole showing water immersion wrinkling

In the 1935 study, however, Lewis and Pickering were studying patients with palsy of the median nerve when they discovered that skin wrinkling did not occur in the areas of the patients' skin normally innervated by the damaged nerve. This suggested that the nervous system plays an essential role in wrinkling, so the phenomenon could not be entirely explained simply by water absorption. Recent research shows that wrinkling is related to vasoconstriction.[17][18] Water probably initiates the wrinkling process by altering the balance of electrolytes in the skin as it diffuses into the hands and soles via their many sweat ducts. This could alter the stability of the membranes of the many neurons that synapse on the many blood vessels underneath skin, causing them to fire more rapidly. Increased neuronal firing causes blood vessels to constrict, decreasing the amount of fluid underneath the skin. This decrease in fluid would cause a decrease in tension, causing the skin to become wrinkly.[19]

This insight resulted in bedside tests for nerve damage and vasoconstriction. Wrinkling is often scored with immersion of the hands for 30 minutes in water or EMLA cream with measurements steps of 5 minutes, and counting the number of visible wrinkles in time. Not all healthy persons have finger wrinkling after immersion, so it would be safe to say that sympathetic function is preserved if finger wrinkling after immersion in water is observed, but if the fingers emerge smooth it cannot be assumed that there is a lesion to the autonomic supply or to the peripheral nerves of the hand.[20]

Other animals with wrinkles

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Examples of wrinkles can be found in various animal species that grow loose, excess skin, particularly when they are young. Several breeds of dog, such as the Pug and the Shar Pei, have been bred to exaggerate this trait. In dogs bred for fighting, this is the result of selection for loose skin, which confers a protective advantage.[21]

Techniques for reducing the appearance of aging wrinkles

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A man receiving a botox injection

Current evidence suggests that tretinoin decreases cohesiveness of follicular epithelial cells, although the exact mode of action is unknown. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells.[22] Tretinoin is better known by the brand name Retin-A.

Topical glycosaminoglycans supplements can help to provide temporary restoration of enzyme balance to slow or prevent matrix breakdown and consequent onset of wrinkle formation. Glycosaminoglycans (GAGs) are produced by the body to maintain structural integrity in tissues and to maintain fluid balance. Hyaluronic acid is a type of GAG that promotes collagen synthesis, repair, and hydration. GAGs serve as a natural moisturizer and lubricant between epidermal cells to inhibit the production of matrix metalloproteinases (MMPs).

Dermal fillers are injectable products frequently used to correct wrinkles, and other depressions in the skin. They are often a kind of soft tissue designed to enable injection into the skin for purposes of improving the appearance. The most common products are based on hyaluronic acid and calcium hydroxylapatite.

Botulinum toxin is a neurotoxin protein produced by the bacterium Clostridium botulinum. Botox is a specific form of botulinum toxin manufactured by Allergan for both therapeutic and cosmetic use. Besides its cosmetic application, Botox is used in the treatment of other conditions including migraine headache and cervical dystonia (spasmodic torticollis) (a neuromuscular disorder involving the head and neck).[23]

Dysport, manufactured by Ipsen, received FDA approval and is now used to treat cervical dystonia as well as glabellar lines in adults. In 2010, another form of botulinum toxin, one free of complexing proteins, became available to Americans. Xeomin received FDA approval for medical indications in 2010 and cosmetic indications in 2011.

Botulinum toxin treats wrinkles by immobilizing the muscles which cause wrinkles. It is not appropriate for the treatment of all wrinkles; it is indicated for the treatment of glabellar lines (between the eyebrows) in adults. Any other usage is not approved by the FDA and is considered off-label use.

Laser resurfacing is FDA-cleared skin resurfacing procedure in which lasers are used to improve the condition of the skin.[citation needed] Two types of lasers are used to reduce the appearance of fine lines and wrinkles on the face; laser ablation, which removes thin layers of skin, and nonablative lasers that stimulate collagen production. Nonablative lasers are less effective than ablative ones but they are less invasive and recovery time is short. After the procedure people experience temporary redness, itching and swelling.

See also

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References

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  1. ^ Danby, FW (Jul–Aug 2010). "Nutrition and aging skin: sugar and glycation". Clin Dermatol. 4. 28 (4): 409–411. doi:10.1016/j.clindermatol.2010.03.018. PMID 20620757.
  2. ^ American Academy of Dermatology. "Causes of Aging". AgingSkinNet. American Academy of Dermatology. Retrieved 5 March 2013.
  3. ^ Cosmetic Procedures for Wrinkles
  4. ^ Anderson, Laurence. 2006. Looking Good, the Australian guide to skin care, cosmetic medicine and cosmetic surgery. AMPCo. Sydney. ISBN 0-85557-044-X.
  5. ^ Schagen, S. K.; Zampeli, V. A.; Makrantonaki, E.; Zouboulis, C. C. (2012). "Discovering the link between nutrition and skin aging". Dermato-Endocrinology. 4 (3): 298–307. doi:10.4161/derm.22876. PMC 3583891. PMID 23467449.
  6. ^ Wang, Jicun; Michelitsch, Thomas; Wunderlin, Arne; Mahadeva, Ravi (2009). "Aging as a consequence of Misrepair—a novel theory of aging". arXiv:0904.0575 [q-bio.TO].
  7. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Aging as a process of accumulation of Misrepairs". arXiv:1503.07163 [q-bio.TO].
  8. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Tissue fibrosis: a principal evidence for the central role of Misrepairs in aging". arXiv:1505.01376 [q-bio.TO].
  9. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
  10. ^ Fulton, James E.; Gaminchi, F. (1999). "Sleep Lines". Dermatol Surg. 25 (1): 59–62. doi:10.1046/j.1524-4725.1999.08073.x. PMID 9935097.
  11. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247 [246]. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
  12. ^ Mark Changizi; Romann Weber; Ritesh Kotecha; Joseph Palazzo (2011). "Are Wet-Induced Wrinkled Fingers Primate Rain Treads?". Brain, Behavior and Evolution. 77 (4): 286–90. doi:10.1159/000328223. PMID 21701145.
  13. ^ Kareklas, Kyriacos; Nettle, Daniel; Smulders, Tom V (January 9, 2013). "Water-induced finger wrinkles improve handling of wet objects". Biol. Lett. 9 (2): 20120999. doi:10.1098/rsbl.2012.0999. PMC 3639753. PMID 23302867.
  14. ^ Haseleu, Julia; Omerbašić, Damir; Frenzel, Henning; Gross, Manfred; Lewin, Gary R. (2014). Goldreich, Daniel (ed.). "Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objects". PLOS ONE. 9 (1): e84949. Bibcode:2014PLoSO...984949H. doi:10.1371/journal.pone.0084949. PMC 3885627. PMID 24416318.
  15. ^ Davis, N. (8 November 2020). "Water-immersion finger-wrinkling improves grip efficiency in handling wet objects". bioRxiv 10.1101/2020.11.07.372631.
  16. ^ "Dr Karl's Homework – Skin Wrinkles in Water (26/1/2000)". Abc.net.au. 2000-01-26. Retrieved 2019-04-30.
  17. ^ Einar P.V. Wilder-Smith; Adeline Chow (2003). "Water-immersion wrinkeling is due to vasoconstriction". Muscle & Nerve. 27 (3): 307–311. doi:10.1002/mus.10323. PMID 12635117. S2CID 45193684.
  18. ^ Einar P. V. Wilder-Smith (2004). "Water immersion wrinkling". Clinical Autonomic Research. 14 (2): 125–131. doi:10.1007/s10286-004-0172-4. PMID 15095056. S2CID 44938772.
  19. ^ H. Zhai, K.P. Whilem H. L. Maibach (2007). Dermatotoxicology. pp. 280–281.
  20. ^ G Alvarez, J Eurolo; P Canales (1980). "Finger wrinkling after immersion in water". British Medical Journal. 281 (6240): 586–587. doi:10.1136/bmj.281.6240.586-a. PMC 1713922. PMID 7427379.
  21. ^ The Dog Encyclopedia: The Definitive Visual Guide. Penguin. 15 August 2023. p. 84. ISBN 978-0-7440-8513-6.
  22. ^ Stefanaki C, Stratigos A, Katsambas A (June 2005). "Topical retinoids in the treatment of photoaging". J Cosmet Dermatol. 4 (2): 130–4. doi:10.1111/j.1473-2165.2005.40215.x. PMID 17166212. S2CID 44702740.
  23. ^ Brin MF, Lew MF, Adler CH, Comella CL, Factor SA, Jankovic J, O'Brien C, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M (1999). "Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia". Neurology. 53 (7): 1431–8. doi:10.1212/WNL.53.7.1431. PMID 10534247.
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Frequently Asked Questions

When choosing between Botox and fillers, consider your desired results. Botox smooths wrinkles, while fillers add volume. They can be safely combined in one treatment plan, but it's crucial to consult with a qualified professional.

You may find that some treatments could be covered by health insurance, but it depends on your plan. They also offer financing plans to help make their services more affordable for patients.

You'll want a practitioner with specialized training in dermatology or plastic surgery and significant experience in administering Botox and fillers. Ensure they're certified and have a track record of safe and effective treatments.