Botox and Fillers Near Downtown New Westminster

Botox and Fillers Near Downtown New Westminster

Non-Invasive Botox

It's not just about looking younger; it's about feeling your best.

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We always advise our clients on how to care for their skin post-treatment to ensure the best possible outcome, but the beauty of Botox is its convenience. How can you best prepare for Botox treatment and what steps should you follow for optimal recovery? Our practitioners aren't only highly skilled but also continually update their knowledge to incorporate the latest advancements in cosmetic treatments. Learn more about Botox and Fillers Near Downtown New Westminster here
At Manhas Health Co., we've seen firsthand how it's not just about the aesthetic improvements but also about boosting our clients' confidence. Side effects, though rare, can occur and include temporary bruising, swelling, or redness at the injection site. Remember, we're here to answer any questions and address concerns, ensuring your experience with Botox at Manhas Health Co. Xeomin Injections is both beneficial and safe. Learn more about Manhas Health Co. here.
At Manhas Health Co, we pride ourselves on our state-of-the-art facilities. Dysport Treatments Staying hydrated and maintaining a healthy skin care routine leading up to your appointment can also enhance your results. After your treatment, we can't stress enough the importance of following our aftercare advice to ensure the best results.
Without these signals, the muscles can't contract, leading to a smoother, softer complexion. At our clinic, we believe that enhancing your natural beauty starts with personalized Botox treatments designed to complement your unique features.

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When considering cosmetic Botox at Manhas Health Co, it's vital to know what the journey entails from start to finish. Botox Injection Cost

Read more about Botox and Fillers Near Downtown New Westminster here

Choosing Manhas Health Co. means choosing a partner who's invested in your beauty and well-being. Choosing Manhas Health Co means opting for excellence, care, and unmatched professionalism. At Manhas Health Co., we're committed to providing answers and personalized care, ensuring that each client's journey towards a fresher facade is both informed and comfortable. We understand that our clients lead busy lives, and finding time for cosmetic treatments can sometimes be challenging.

This ensures that you're receiving the safest and most effective treatment possible. Botox Injections Near You We'll give you detailed aftercare instructions to ensure a smooth recovery. Anticipation builds as you get ready for your Botox session at Manhas Health Co., marking the first step towards achieving your desired aesthetic goals.

You'll need to provide some basic information such as your name, contact number, and any specific concerns or areas you'd like to focus on during your Botox treatment. At Manhas Health Co, we offer a wide range of Botox procedures tailored to meet individual needs and aesthetic goals. New Westminster Botox Clinics One of our clients, Sarah, shared, 'After my sessions at Manhas Health Co., I noticed a significant reduction in my forehead lines.

While the idea of incorporating Botox into one's wellness routine might raise some eyebrows, the reasons behind its growing popularity and why Manhas Health Co. is the go-to clinic for such services are compelling stories we're eager to share.

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We believe in providing value and exceptional service, making your experience as comfortable and satisfying as possible. At Manhas Health Co., our expertise in delivering high-quality Cosmetic Botox services sets us apart in the wellness industry.

Cheek fillers New Westminster

Entity Name Description Source
Botulinum toxin Description for Botulinum toxin Source
Skeletal muscle Description for Skeletal muscle Source
Eyelid Description for Eyelid Source
Eye drop Description for Eye drop Source
Injectable filler Description for Injectable filler Source
Marionette lines Description for Marionette lines Source
Lip Description for Lip Source
Dermatology Description for Dermatology Source
Mohs surgery Description for Mohs surgery Source
Skin cancer Description for Skin cancer Source
Varicose veins Description for Varicose veins Source
Melanocytic nevus Description for Melanocytic nevus Source
Collagen induction therapy Description for Collagen induction therapy Source
Platelet-rich plasma Description for Platelet-rich plasma Source
Pattern hair loss Description for Pattern hair loss Source
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New Westminster Description for New Westminster Source
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Rhinoplasty Description for Rhinoplasty Source
Masseter muscle Description for Masseter muscle Source
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Under eye fillers New Westminster

Richard Clement Moody arrived in British Columbia in December 1858, at the head of the Royal Engineers, Columbia Detachment, having been hand picked to "found a second England on the shores of the Pacific".  Moody "wanted to build a city of beauty in the wilderness" and planned his city as an iconic visual metaphor for British dominance, "styled and located with the objective of reinforcing the authority of the Crown and of the robe  Subsequent to the enactment of the Pre-emption Act of 1860, Moody settled the Lower Mainland and selected the site and founded the new capital, New Westminster. Moody and the Royal Engineers were trained in settlement and selected the site because of its defensibility: it was farther from the American border than the site of the colony's proclamation, Fort Langley, possessed "great facilities for communication by water, as well as by future great trunk railways into the interior and possessed an excellent port  Moody was also struck by the majestic beauty of the site, writing in his letter to Blackwood:

New Westminster cosmetic injectables

Nearby Tourist Attractions

Ron McLean Park

Tourist attraction, Park
Ron McLean Park, 7820 Hedley Ave, Burnaby, BC V5E 2R3
Community park with a kids' playground, baseball field & courts for tennis & basketball.

Byrne Creek Ravine Park

Tourist attraction, Park
Byrne Creek Ravine Park, 6555 Byrnepark Dr, Burnaby, BC V5E 4L4
Wooded natural area with a winding creek, trails for hiking & dog-walking & a baseball diamond.

Burnaby Blues & Roots Festival

Tourist attraction
Burnaby Blues & Roots Festival, Burnaby, BC V5G 3T1

Burnaby Mountain Biking and Hiking Trails

Tourist attraction, Hiking area
Burnaby Mountain Biking and Hiking Trails, University Dr E, Burnaby, BC V5A 4Y8


Citations and other links

Botox for smile lines Botox and Fillers Near Downtown New Westminster

Understanding the cost and exploring payment options for cosmetic Botox is crucial for anyone considering this treatment at Manhas Health Co. Botox Cosmetic Specialists We're experts at subtly smoothing away fine lines and preventing deeper creases from forming, all while ensuring your face retains its natural expressions. They're here not just to perform procedures, but to offer guidance, answer questions, and ensure you feel comfortable and informed every step of the way. For anyone curious about the transformative potential of Botox and how it could redefine their approach to aging gracefully, the insights from real client testimonials and an in-depth look into the consultation process at Manhas Health Co. might just be the guidance needed to take the next step. Our team of experts, known for their professionalism and personalized approach, ensures that every treatment plan is tailored to meet the unique needs and expectations of our clients.

Most importantly, we've seen how these changes can uplift someone's spirit. Next, we've expanded our services to include Botox for crow's feet. Sun protection is another key aspect we never overlook. Botox For Forehead Rejuvenation Choosing Botox at Manhas Health Co. means opting for a smoother, more refreshed look with a team committed to your care and satisfaction.

Our aim is to help you achieve a refreshed, more youthful appearance that still looks like you. Moreover, we understand that every individual's needs are unique. We've seen firsthand how this treatment can smooth out wrinkles, erase fine lines, and restore a youthful vibrancy that many of us start to miss as the years pass by. It's not just about looking younger; it's about feeling revitalized and more confident in one's skin.

After my treatment at Manhas Health Co., I not only look refreshed but feel a surge of confidence. It's important to us that you feel informed and comfortable before proceeding. We often think of Botox as a corrective treatment, but it's just as valuable as a proactive one. Some clients might experience headaches or flu-like symptoms for a short period post-treatment.

Botox for smile lines Botox and Fillers Near Downtown New Westminster
Advanced wrinkle therapy Botox and Fillers Near Downtown New Westminster

Advanced wrinkle therapy Botox and Fillers Near Downtown New Westminster

Trust us to provide you with a Botox treatment that not only meets but exceeds your expectations, highlighting your natural beauty in the best possible light. Lastly, applying a cold pack to the treated areas can help reduce any swelling or bruising. Moreover, we're committed to ensuring safety and comfort throughout the process. And we're always here to answer any questions, providing a level of care and support that's hard to find elsewhere. We're here to guide you through the aftercare process and answer any questions, ensuring you're delighted with your rejuvenated skin.

How can we ensure your Botox treatment is as safe and effective as possible? At Manhas Health Co. in Botox and Fillers Near Downtown New Westminster, we're bringing beauty back with our bespoke Botox treatments, tailored to transform your skin. Another advantage is the non-invasive nature of Botox. Browsing through the gallery, you'll notice the precision in our work, the natural-looking results, and the attention to detail that sets us apart.

It might take a few days to see the full effects of the treatment, but trust us, it's worth the wait. At Manhas Health Co., we're dedicated to providing our clients with the highest level of care and expertise in cosmetic Botox treatments. Additionally, staying out of direct sunlight and high heat environments such as saunas or hot showers can help maintain the integrity of your treatment results. We've thoroughly researched and can assure you that when administered by qualified professionals, Botox is both safe and effective.

Our team is committed to providing personalized care that aligns with your unique desires and health objectives. We've seen a growing interest in this procedure at Manhas Health Co., where our clients are increasingly eager to rejuvenate their appearance without undergoing invasive surgeries. Whether you're looking to smooth out fine lines and wrinkles, reduce excessive sweating, or treat chronic migraines, we've got you covered.

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We're committed to ensuring that your experience is as comfortable and satisfying as possible.

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We're excited to offer Cosmetic Botox because it's a quick, minimally invasive procedure that can make a significant difference in how people perceive themselves. We'll discuss your medical history, any medications you're taking, and assess your skin to ensure Botox is the right choice for you. We're committed to creating a welcoming and stress-free environment, so you'll feel at ease throughout the process. We believe that communication is key to achieving the best outcomes. At Manhas Health Co., we're committed to providing an experience that's as exceptional as the results we deliver.

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Our team of professionals is trained in the latest techniques to ensure that each session is tailored to meet individual needs and expectations. Following your Botox treatment at Manhas Health Co., we'll guide you through the aftercare process to ensure optimal results and a smooth recovery. At Manhas Health Co., we're committed to ensuring that your cosmetic Botox experience not only meets but also exceeds your expectations. This personalized approach ensures that we can target just the right areas, with the right amount of Botox, to achieve natural-looking results that enhance your features without altering your natural expressions.

Hydrated skin responds better to Botox, and a good skincare regimen ensures that your skin is in the best condition possible. Furthermore, the convenience doesn't stop at the time it takes to perform the procedure. This is where frown lines occur, and Botox can significantly reduce these marks of concentration or concern, contributing to a friendlier, more approachable appearance. The procedure itself is quick, usually taking no more than 20 minutes.

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John, another satisfied client, mentioned, 'The team at Manhas Health Co. Botox Benefits made me feel comfortable from the start. It's crucial not to rub or massage the treated areas for at least 24 hours; this prevents the Botox from spreading to unintended muscles. At Manhas Health Co., we've seen firsthand how Botox can significantly reduce the appearance of wrinkles, offering a more youthful look that our clients love. The minimal downtime associated with Botox at Manhas Health Co. means that achieving a refreshed and rejuvenated appearance doesn't have to disrupt your schedule.

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Cheek fillers Botox and Fillers Near Downtown New Westminster

They're not just about the treatments but ensuring you're comfortable and informed throughout the process.” We're here to support our clients, not just aesthetically, but by providing a caring and professional environment. We're excited for you to see the difference Manhas Health Co. can make in your life. After the injections, we'll provide you with aftercare instructions to ensure the best possible results and minimize any potential side effects. We understand that everyone's skin is unique, which is why we offer personalized consultations. Understanding that each patient has unique needs, we create personalized Botox treatment plans to achieve the best possible outcomes.

That's why we don't just offer a one-size-fits-all approach. We also make sure to stay upright for several hours post-treatment to assist with this. We'll also include a reminder closer to the date, so you won't forget. We then craft a personalized treatment plan, ensuring the results align with their desires.

Our goal is to make your experience as comfortable and satisfying as possible. One client mentioned, “After my first session at Manhas Health Co., I noticed a significant reduction in my forehead lines. We're always amazed at how a few small injections can make such a significant difference. By sticking to these before and after care tips, we're confident you'll love your refreshed look.

We're here to guide you through the financial aspects, ensuring clarity and ease of access to our services. Our Botox services extend to addressing excessive sweating, a condition known as hyperhidrosis, which can be life-changing for those who've struggled with it. This ensures that our treatment plans aren't only effective but also safe for each individual.

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We're here to listen and provide you with the information you need to make an informed decision.

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These stories aren't just about the aesthetic improvements; they're about the newfound confidence and joy our clients experience. We understand that life can be unpredictable, so we've designed our booking process to be flexible. We're here to guide you through understanding the full spectrum of benefits that cosmetic Botox offers, including our competitive cost and flexible payment options. We've gathered a few tips to ensure you're fully prepared for the treatment day. We know that everyone's skin and cosmetic goals differ, which is why we don't take a one-size-fits-all approach.
We've dedicated ourselves to not just meeting, but exceeding the expectations of our clients, ensuring each experience is tailored to their individual needs. You're in good hands with us at Manhas Health Co. Our priority is to accommodate your needs while ensuring you feel confident and informed every step of the way. We're here to guide you through each step, ensuring your experience is as comfortable and satisfying as possible. Botox For Crow'S Feet New Westminster
At Manhas Health Co., we're more than just a clinic; we're a partner in your journey to feeling and looking your best. Our professionals are highly trained in administering Botox, guaranteeing not just effective but also natural-looking results. It's not just about looking younger; it's also about feeling better in your skin. Our goal is to ensure everyone leaves feeling informed and excited about their Botox journey.
Beyond the convenience of minimal downtime, we're proud to highlight that Botox treatments at Manhas Health Co. also offer long-lasting results that our clients love. Recognizing the uniqueness of each individual's needs, we customize every Cosmetic Botox treatment plan to ensure optimal results. That's why we're thrilled to offer a solution that not only delivers remarkable results but also respects our clients' time. We use a fine needle for the injections, making the process as comfortable as possible.

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Military Policlinic in Legionowo, Poland

A clinic (or outpatient clinic or ambulatory care clinic) is a health facility that is primarily focused on the care of outpatients. Clinics can be privately operated or publicly managed and funded. They typically cover the primary care needs of populations in local communities, in contrast to larger hospitals which offer more specialized treatments and admit inpatients for overnight stays.

Most commonly, the English word clinic refers to a general practice, run by one or more general practitioners offering small therapeutic treatments, but it can also mean a specialist clinic. Some clinics retain the name "clinic" even while growing into institutions as large as major hospitals or becoming associated with a hospital or medical school.

Etymology

[edit]
The entrance to a surgery clinic in Greenwich, London

The word clinic derives from Ancient Greek κλίνειν klinein meaning to slope, lean or recline. Hence κλίνη klinē is a couch or bed and κλινικός klinikos is a physician who visits his patients in their beds.[1] In Latin, this became clīnicus.[2][3]

An early use of the word clinic was "one who receives baptism on a sick bed".[4]

Overview

[edit]
A medpunkt (health care access point) delivers primary health care to the residents of the village of Veliki Vrag, Russia.

Clinics are often associated with a general medical practice run by one or several general practitioners. Other types of clinics are run by the type of specialist associated with that type: physical therapy clinics by physiotherapists and psychology clinics by clinical psychologists, and so on for each health profession. (This can even hold true for certain services outside the medical field: for example, legal clinics are run by lawyers.)

Some clinics are operated in-house by employers, government organizations, or hospitals, and some clinical services are outsourced to private corporations which specialize in providing health services. In China, for example, owners of such clinics do not have formal medical education. There were 659,596 village clinics in China in 2011.[5]

Health care in India, China, Russia and Africa is provided to those regions' vast rural areas by mobile health clinics or roadside dispensaries, some of which integrate traditional medicine. In India these traditional clinics provide ayurvedic medicine and unani herbal medical practice. In each of these countries, traditional medicine tends to be a hereditary practice.

Function

[edit]
Policlinic in Karl-Marx-Stadt, German Democratic Republic

The function of clinics differs from country to country. For instance, a local general practice run by a single general practitioner provides primary health care and is usually run as a for-profit business by the owner, whereas a government-run specialist clinic may provide subsidized or specialized[dubiousdiscuss] health care.

Some clinics serve as a place for people with injuries or illnesses to be seen by a triage nurse or other health worker. In these clinics, the injury or illness may not be serious enough to require a visit to an emergency room (ER), but the person can be transferred to one if needed.

Treatment at these clinics is often less expensive than it would be at a casualty department. Also, unlike an ER these clinics are often not open on a 24/7/365 basis. They sometimes have access to diagnostic equipment such as X-ray machines, especially if the clinic is part of a larger facility. Doctors at such clinics can often refer patients to specialists if the need arises.[6]

Large outpatient clinics

[edit]
Children Policlinic in Novokosino District of Moscow

Large outpatient clinics vary in size, but can be as large as hospitals.

Function

[edit]

Typical large outpatient clinics house general medical practitioners (GPs) such as doctors and nurses to provide ambulatory care and some acute care services but lack the major surgical and pre- and post-operative care facilities commonly associated with hospitals.

Policlinic in Vilnius-Karoliniškės, Lithuania

Besides GPs, if a clinic is a polyclinic, it can house outpatient departments of some medical specialties, such as gynecology, dermatology, ophthalmology, otolaryngology, neurology, pulmonology, cardiology, and endocrinology. In some university cities, polyclinics contain outpatient departments for the entire teaching hospital in one building.

Internationally

[edit]
Policlinic in Písek, Czech Republic

Large outpatient clinics are a common type of healthcare facility in many countries, including France, Germany (long tradition), Switzerland, and most of the countries of Central and Eastern Europe (often using a mixed Soviet-German model), as well as in former Soviet republics such as Russia and Ukraine;[7] and in many countries across Asia and Africa.[8]

In Europe, especially in the Central and Eastern Europe, bigger outpatient health centers, commonly in cities and towns, are called policlinics (derived from the word polis, not from poly-).

Recent[when?] Russian governments have attempted to replace the policlinic model introduced during Soviet times with a more western model. However, this has failed.[9]

In the Czech Republic, many policlinics were privatized or leasehold and decentralized in the post-communist era: some of them are just lessors and coordinators of a healthcare provided by private doctor's offices in the policlinic building.[10]

India has also set up huge numbers of polyclinics for former defense personnel. The network envisages 426 polyclinics in 343 districts of the country which will benefit about 33 lakh (3.3 million) ex-servicemen residing in remote and far-flung areas.[11]

Policlinics are also the backbone of Cuba's primary care system and have been credited with a role in improving that nation's health indicators.[12]

Mobile clinics

[edit]
Hinduja National Hospital's mobile clinic
A mobile health clinic operated from a truck

Providing health services through mobile clinics provides accessible healthcare services to these remote areas that have yet to make their way in the politicized space. For example, mobile clinics have proved helpful in dealing with new settlement patterns in Costa Rica. Before foreign aid organizations or the state government became involved in healthcare, Costa Rica's people managed their own health maintenance and protection.[13] People relied on various socio-cultural adaptations and remedies to prevent illnesses, such as personal hygiene and settlement patterns.[13] When new settlements that sprang up along the coast became "artificial" communities, and due to lack of traditional home healing practices here, alternative methods such as mobile clinics had to be implemented in these communities for the protection and prevention of diseases.[13]

A study done in rural Namibia revealed the health changes of orphans, vulnerable children and non-vulnerable children (OVC) visiting a mobile clinic where health facilities are far from the remote villages.[14] Over 6 months, information on immunization status, diagnosis of anemia, skin and intestinal disorders, nutrition, dental disorders was collected and showed that visits to mobile clinics improved the overall health of children that visited regularly. It concluded that specified "planning of these programs in areas with similarly identified barriers may help correct the health disparities among Namibian OVC and could be a first step in improving child morbidity and mortality in difficult-to-reach rural areas."[14]

A mobile clinic run from a pickup truck in Yemen

Food supplementation in the context of routine mobile clinic visits also shows to have improved the nutritional status of children, and it needs further exploration as a way to reduce childhood malnutrition in resource-scarce areas. A cross-sectional study focussed on comparing acute and chronic undernutrition rates prior to and after a food-supplementation program as an adjunct to routine health care for children of migrant workers residing in rural communities in the Dominican Republic.[15] Rates of chronic undernutrition decreased from 33% to 18% after the initiation of the food-supplementation program and shows that the community members attending the mobile clinics are not just passively receiving the information but are incorporating it and helping keep their children nourished.[15]

Types

[edit]
Storefront clinic in Manhattan

There are many different types of clinics providing outpatient services. Such clinics may be public (government-funded) or private medical practices.

  • A CLSC are in Quebec; they are a type of free clinic funded by the provincial government; they provide service not covered by Canada's healthcare plan including social workers
  • In the United States, a free clinic provides free or low-cost healthcare for those with little or without insurance.
  • A retail-based clinic is housed in supermarkets and similar retail outlets providing walk-in health care, which may be staffed by nurse practitioners.
  • A general out-patient clinic offers general diagnoses or treatments without an overnight stay.
  • A polyclinic or policlinic provides a range of healthcare services (including diagnostics) without need of an overnight stay
  • A specialist clinic provides advanced diagnostic or treatment services for specific diseases or parts of the body. This type contrasts with general out-patient clinics.

See also

[edit]

References

[edit]
  1. ^ κλινικός in A Greek–English Lexicon. Retrieved 18 September 2016.
  2. ^ clinicus in A Latin Dictionary. Retrieved 18 September 2016.
  3. ^ Partridge, Eric. Origins: A short etymological dictionary of modern English. Book Club Associates, 1966.
  4. ^ Clinic, Webster's Revised Unabridged Dictionary, 1913.
  5. ^ "Statistical Communiqué on the 2011 National Economic and Social Development". stats.gov.cn. National Bureau of Statistics of China. 22 February 2012. Archived from the original on 6 April 2012. Retrieved 5 September 2012.
  6. ^ "Clinic search engine tools to find the right Clinic". 123 clinic. Retrieved 15 December 2016.
  7. ^ NLH – Health Management – Policlinics. Retrieved 3 July 2008.[permanent dead link]
  8. ^ Google
  9. ^ Ershova I, Rider O, Gorelov V (December 2007). "Policlinics in London". Lancet. 370 (9603): 1890–1. doi:10.1016/S0140-6736(07)61793-0. PMID 18068500. S2CID 43512994.
  10. ^ David Rath: Trnitá cesta privatizace českého zdravotnictví, Hospodářské noviny, 10 September 1996
  11. ^ "199 Additional Polyclinics For Ex-Servicemen". The Hindu. Chennai, India. 26 May 2010.
  12. ^ Cuba's primary health care revolution: 30 years on, Bulletin of the World Health Organization
  13. ^ a b c Morgan, Lynn M. (February 1993). Community Participation in Health: The Politics of Primary Care in Costa Rica. doi:10.1017/CBO9780511558092. ISBN 978-0-521-41898-0. Retrieved 8 May 2020. cite book: |website= ignored (help)
  14. ^ a b Aneni, Ehimen; De Beer, Ingrid H.; Hanson, Laura; Rijnen, Bas; Brenan, Alana T.; Feeley, Frank G. (2013). "Mobile primary healthcare services and health outcomes of children in rural Namibia". Rural and Remote Health. 13 (3): 2380. ISSN 1445-6354. PMID 24016257.
  15. ^ a b Parikh, Kavita; Marein-Efron, Gabriela; Huang, Shirley; O'Hare, Geraldine; Finalle, Rodney; Shah, Samir S. (September 2010). "Nutritional Status of Children after a Food-Supplementation Program Integrated with Routine Health Care through Mobile Clinics in Migrant Communities in the Dominican Republic". The American Journal of Tropical Medicine and Hygiene. 83 (3): 559–564. doi:10.4269/ajtmh.2010.09-0485. ISSN 0002-9637. PMC 2929051. PMID 20810820.

Wrinkles on the face and hands are a typical sign of aging

A wrinkle, also known as a rhytid, is a fold, ridge or crease in an otherwise smooth surface, such as on skin or fabric. Skin wrinkles typically appear as a result of ageing processes such as glycation,[1] habitual sleeping positions,[2] loss of body mass, sun damage,[3] or temporarily, as the result of prolonged immersion in water. Age wrinkling in the skin is promoted by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors.[4] In humans, it can also be prevented to some degree by avoiding excessive solar exposure and through diet (in particular through consumption of carotenoids, tocopherols and flavonoids, vitamins (A, C, D and E), essential omega-3-fatty acids, certain proteins and lactobacilli).[5]

Skin

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Causes for aging wrinkles

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A woman of European origin with facial wrinkles

Development of facial wrinkles is a kind of fibrosis of the skin. Misrepair-accumulation aging theory suggests that wrinkles develop from incorrect repairs of injured elastic fibers and collagen fibers.[6][7][8] Repeated extensions and compressions of the skin cause repeated injuries of extracellular fibers in derma. During the repairing process, some of the broken elastic fibers and collagen fibers are not regenerated and restored but replaced by altered fibers. When an elastic fiber is broken in an extended state, it may be replaced by a "long" collagen fiber. Accumulation of "long" collagen fibers makes part of the skin looser and stiffer, and as a consequence, a big fold of skin appears. When a "long" collagen is broken in a compressed state, it may be replaced by a "short" collagen fiber. The "shorter" collagen fibers will restrict the extension of "longer" fibers, and make the “long" fibers in a folding state permanently. A small fold, namely a permanent wrinkle, then appears.

Sleep wrinkles

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Sleep wrinkles are created and reinforced when the face is compressed against a pillow or bed surface in side or stomach sleeping positions during sleep.[9] They appear in predictable locations due to the underlying superficial musculoaponeurotic system (SMAS), and are usually distinct from wrinkles of facial expression.[10] As with wrinkles of facial expression, sleep wrinkles can deepen and become permanent over time, unless the habitual sleeping positions which cause the wrinkles are altered.[11]

Water-immersion wrinkling

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A wrinkled finger after a warm bath

The wrinkles that occur in skin over prolonged exposure to water are sometimes referred to as pruney fingers or water aging. This is a temporary skin condition where the skin on the palms of the hand or feet becomes wrinkly. This wrinkling response may have imparted an evolutionary benefit by providing improved traction in wet conditions,[12] and a better grasp of wet objects.[13] These results were called into question by a 2014 study that failed to reproduce any improvement of handling wet objects with wrinkled fingertips.[14] However, a 2020 study of gripping efficiency found that wrinkles decreased the force required to grip wet objects by 20%, supporting the traction hypothesis.[15]

Prior to a 1935 study, the common explanation was based on water absorption in the keratin-laden epithelial skin when immersed in water,[16] causing the skin to expand and resulting in a larger surface area, forcing it to wrinkle. Usually the tips of the fingers and toes are the first to wrinkle because of a thicker layer of keratin and an absence of hairs which secrete the protective oil called sebum.

Adult sole showing water immersion wrinkling

In the 1935 study, however, Lewis and Pickering were studying patients with palsy of the median nerve when they discovered that skin wrinkling did not occur in the areas of the patients' skin normally innervated by the damaged nerve. This suggested that the nervous system plays an essential role in wrinkling, so the phenomenon could not be entirely explained simply by water absorption. Recent research shows that wrinkling is related to vasoconstriction.[17][18] Water probably initiates the wrinkling process by altering the balance of electrolytes in the skin as it diffuses into the hands and soles via their many sweat ducts. This could alter the stability of the membranes of the many neurons that synapse on the many blood vessels underneath skin, causing them to fire more rapidly. Increased neuronal firing causes blood vessels to constrict, decreasing the amount of fluid underneath the skin. This decrease in fluid would cause a decrease in tension, causing the skin to become wrinkly.[19]

This insight resulted in bedside tests for nerve damage and vasoconstriction. Wrinkling is often scored with immersion of the hands for 30 minutes in water or EMLA cream with measurements steps of 5 minutes, and counting the number of visible wrinkles in time. Not all healthy persons have finger wrinkling after immersion, so it would be safe to say that sympathetic function is preserved if finger wrinkling after immersion in water is observed, but if the fingers emerge smooth it cannot be assumed that there is a lesion to the autonomic supply or to the peripheral nerves of the hand.[20]

Other animals with wrinkles

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Examples of wrinkles can be found in various animal species that grow loose, excess skin, particularly when they are young. Several breeds of dog, such as the Pug and the Shar Pei, have been bred to exaggerate this trait. In dogs bred for fighting, this is the result of selection for loose skin, which confers a protective advantage.[21]

Techniques for reducing the appearance of aging wrinkles

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A man receiving a botox injection

Current evidence suggests that tretinoin decreases cohesiveness of follicular epithelial cells, although the exact mode of action is unknown. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells.[22] Tretinoin is better known by the brand name Retin-A.

Topical glycosaminoglycans supplements can help to provide temporary restoration of enzyme balance to slow or prevent matrix breakdown and consequent onset of wrinkle formation. Glycosaminoglycans (GAGs) are produced by the body to maintain structural integrity in tissues and to maintain fluid balance. Hyaluronic acid is a type of GAG that promotes collagen synthesis, repair, and hydration. GAGs serve as a natural moisturizer and lubricant between epidermal cells to inhibit the production of matrix metalloproteinases (MMPs).

Dermal fillers are injectable products frequently used to correct wrinkles, and other depressions in the skin. They are often a kind of soft tissue designed to enable injection into the skin for purposes of improving the appearance. The most common products are based on hyaluronic acid and calcium hydroxylapatite.

Botulinum toxin is a neurotoxin protein produced by the bacterium Clostridium botulinum. Botox is a specific form of botulinum toxin manufactured by Allergan for both therapeutic and cosmetic use. Besides its cosmetic application, Botox is used in the treatment of other conditions including migraine headache and cervical dystonia (spasmodic torticollis) (a neuromuscular disorder involving the head and neck).[23]

Dysport, manufactured by Ipsen, received FDA approval and is now used to treat cervical dystonia as well as glabellar lines in adults. In 2010, another form of botulinum toxin, one free of complexing proteins, became available to Americans. Xeomin received FDA approval for medical indications in 2010 and cosmetic indications in 2011.

Botulinum toxin treats wrinkles by immobilizing the muscles which cause wrinkles. It is not appropriate for the treatment of all wrinkles; it is indicated for the treatment of glabellar lines (between the eyebrows) in adults. Any other usage is not approved by the FDA and is considered off-label use.

Laser resurfacing is FDA-cleared skin resurfacing procedure in which lasers are used to improve the condition of the skin.[citation needed] Two types of lasers are used to reduce the appearance of fine lines and wrinkles on the face; laser ablation, which removes thin layers of skin, and nonablative lasers that stimulate collagen production. Nonablative lasers are less effective than ablative ones but they are less invasive and recovery time is short. After the procedure people experience temporary redness, itching and swelling.

See also

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References

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  1. ^ Danby, FW (Jul–Aug 2010). "Nutrition and aging skin: sugar and glycation". Clin Dermatol. 4. 28 (4): 409–411. doi:10.1016/j.clindermatol.2010.03.018. PMID 20620757.
  2. ^ American Academy of Dermatology. "Causes of Aging". AgingSkinNet. American Academy of Dermatology. Retrieved 5 March 2013.
  3. ^ Cosmetic Procedures for Wrinkles
  4. ^ Anderson, Laurence. 2006. Looking Good, the Australian guide to skin care, cosmetic medicine and cosmetic surgery. AMPCo. Sydney. ISBN 0-85557-044-X.
  5. ^ Schagen, S. K.; Zampeli, V. A.; Makrantonaki, E.; Zouboulis, C. C. (2012). "Discovering the link between nutrition and skin aging". Dermato-Endocrinology. 4 (3): 298–307. doi:10.4161/derm.22876. PMC 3583891. PMID 23467449.
  6. ^ Wang, Jicun; Michelitsch, Thomas; Wunderlin, Arne; Mahadeva, Ravi (2009). "Aging as a consequence of Misrepair—a novel theory of aging". arXiv:0904.0575 [q-bio.TO].
  7. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Aging as a process of accumulation of Misrepairs". arXiv:1503.07163 [q-bio.TO].
  8. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Tissue fibrosis: a principal evidence for the central role of Misrepairs in aging". arXiv:1505.01376 [q-bio.TO].
  9. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
  10. ^ Fulton, James E.; Gaminchi, F. (1999). "Sleep Lines". Dermatol Surg. 25 (1): 59–62. doi:10.1046/j.1524-4725.1999.08073.x. PMID 9935097.
  11. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247 [246]. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
  12. ^ Mark Changizi; Romann Weber; Ritesh Kotecha; Joseph Palazzo (2011). "Are Wet-Induced Wrinkled Fingers Primate Rain Treads?". Brain, Behavior and Evolution. 77 (4): 286–90. doi:10.1159/000328223. PMID 21701145.
  13. ^ Kareklas, Kyriacos; Nettle, Daniel; Smulders, Tom V (January 9, 2013). "Water-induced finger wrinkles improve handling of wet objects". Biol. Lett. 9 (2): 20120999. doi:10.1098/rsbl.2012.0999. PMC 3639753. PMID 23302867.
  14. ^ Haseleu, Julia; Omerbašić, Damir; Frenzel, Henning; Gross, Manfred; Lewin, Gary R. (2014). Goldreich, Daniel (ed.). "Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objects". PLOS ONE. 9 (1): e84949. Bibcode:2014PLoSO...984949H. doi:10.1371/journal.pone.0084949. PMC 3885627. PMID 24416318.
  15. ^ Davis, N. (8 November 2020). "Water-immersion finger-wrinkling improves grip efficiency in handling wet objects". bioRxiv 10.1101/2020.11.07.372631.
  16. ^ "Dr Karl's Homework – Skin Wrinkles in Water (26/1/2000)". Abc.net.au. 2000-01-26. Retrieved 2019-04-30.
  17. ^ Einar P.V. Wilder-Smith; Adeline Chow (2003). "Water-immersion wrinkeling is due to vasoconstriction". Muscle & Nerve. 27 (3): 307–311. doi:10.1002/mus.10323. PMID 12635117. S2CID 45193684.
  18. ^ Einar P. V. Wilder-Smith (2004). "Water immersion wrinkling". Clinical Autonomic Research. 14 (2): 125–131. doi:10.1007/s10286-004-0172-4. PMID 15095056. S2CID 44938772.
  19. ^ H. Zhai, K.P. Whilem H. L. Maibach (2007). Dermatotoxicology. pp. 280–281.
  20. ^ G Alvarez, J Eurolo; P Canales (1980). "Finger wrinkling after immersion in water". British Medical Journal. 281 (6240): 586–587. doi:10.1136/bmj.281.6240.586-a. PMC 1713922. PMID 7427379.
  21. ^ The Dog Encyclopedia: The Definitive Visual Guide. Penguin. 15 August 2023. p. 84. ISBN 978-0-7440-8513-6.
  22. ^ Stefanaki C, Stratigos A, Katsambas A (June 2005). "Topical retinoids in the treatment of photoaging". J Cosmet Dermatol. 4 (2): 130–4. doi:10.1111/j.1473-2165.2005.40215.x. PMID 17166212. S2CID 44702740.
  23. ^ Brin MF, Lew MF, Adler CH, Comella CL, Factor SA, Jankovic J, O'Brien C, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M (1999). "Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia". Neurology. 53 (7): 1431–8. doi:10.1212/WNL.53.7.1431. PMID 10534247.
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